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Stem Cell Transplant Game Information
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Recommended Grade Levels:  10-12+ (ages 16-18+)


Run Time:  25-30 minutes


Story Line:  Help Dr. Alice Duncanson treat patients who have leukemia that has not responded to chemotherapy.  Assist as she: 1)  works to find a match, 2) then harvests bone marrow from a donor, and 3) transplants the stem cells into two patients. Learn about the immune system, stem cells, transplant donor matching and more!  Worksheets and a quiz are included in the teacher's guide.


Technical:  This is a Flash game, so you will need the Puffin Academy Browser if you are going to play this game on a mobile device.   We also recommend having ear buds to play the activity in class or in public areas.  Speakers are fine for home use. 


Screen Shots:






Educational Standards:  

High School Life Science

HS-LS1-1 Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential functions of life through systems of specialized cells.

HS-LS1-4 Use a model to illustrate the role of cellular division (mitosis) and differentiation in producing and maintaining complex organisms.

High School Engineering, Technology, and the Applications of Science

HS-ETS1-1. Analyze a major global challenge to specify qualitative and quantitative criteria and constraints for solutions that account for societal needs and wants.

High School ELA

RST.9-10.2 Determine the central ideas or conclusions of a text; trace the text’s explanation or depiction of a complex process, phenomenon, or concept; provide an accurate summary of the text.

RST.9-10.3 Follow precisely a complex multistep procedure when carrying out experiments, taking measurements, or performing technical tasks, attending to special cases or exceptions defined in the text.

RST.9-10.4 Determine the meaning of symbols, key terms, and other domain-specific words and phrases as they are used in a specific scientific or technical context relevant to grades 9–10 texts and topics.

RST.9-10.9 Compare and contrast findings presented in a text to those from other sources (including their own experiments), noting when the findings support or contradict previous explanations or accounts.

RST.11-12.3 Follow precisely a complex multistep procedure when carrying out experiments, taking measurements, or performing technical tasks; analyze the specific results based on explanations in the text.

RST.11-12.4 Determine the meaning of symbols, key terms, and other domain-specific words and phrases as they are used in a specific scientific or technical context relevant to grades 11–12 texts and topics.

RST.11-12.5 Analyze how the text structures information or ideas into categories or hierarchies, demonstrating understanding of the information or ideas.

RST.11-12.7 Integrate and evaluate multiple sources of information presented in diverse formats and media (e.g., quantitative data, video, multimedia) in order to address a question or solve a problem.

RST.11-12.9 Synthesize information from a range of sources (e.g., texts, experiments, simulations) into a coherent understanding of a process, phenomenon, or concept, resolving conflicting information when possible.

Ohio Science Standards – Benchmarks and Indicators

Science & Technology - Grade 10:

Life Sciences

Historical Perspectives and Scientific Revolutions

27.  Describe advances in life sciences that have important long-lasting effects on science and society (e.g., biological evolution, germ theory, biotechnology and discovering germs).

28.  Analyze and investigate emerging scientific issues (e.g., genetically modified food, stem cell research, genetic research and cloning).

Science and Technology

Understanding Technology

1.     Cite examples of ways that scientific inquiry is driven by the desire to understand the natural world and how technology is driven by the need to meet human needs and solve human problems.

2.     Describe examples of scientific advances and emerging technologies and how they may impact society.

Scientific Inquiry

Doing Scientific Inquiry

1.     Research and apply appropriate safety precautions when designing and conducting scientific investigations (e.g. OSHA, MSDS, eyewash, goggles and ventilation).

2.     Present scientific findings using clear language, accurate data, appropriate graphs, tables, maps and available technology.

4.     Draw conclusions from inquiries based on scientific knowledge and principles, the use of logic and evidence (data) from investigations.

Scientific Ways of Knowing

Science and Society

7.     Investigate how the knowledge, skills and interests learned in science classes apply to the careers students plan to pursue.

Life Science - Grade 11:

Characteristics and Structure of Life

1.     Describe how the maintenance of a relatively stable internal environment is required for the continuation of life, and explain how stability is challenged by changing physical, chemical and environmental conditions as well as the presence of pathogens.

Scientific Inquiry

Doing Scientific Inquiry

2.     Evaluate assumptions that have been used in reaching scientific conclusions.

3.     Design and carry out scientific inquiry (investigation), communicate and critique results through peer review.

5.     Summarize data and construct a reasonable argument based on those data and other known information.

Scientific Ways of Knowing

Science and Society

8.     Explain that the decision to develop a new technology is influenced by societal opinions and demands and by cost benefit considerations.

10.  Research the role of science and technology in careers that students plan to pursue.


Science as Inquiry:

·        Abilities necessary to do scientific inquiry

·        Understandings about scientific inquiry

Life Science:

·        The cell

Science and Technology

·        Understandings about science and technology

Science in Personal and Social Perspectives:

·        Science and technology in local, national, and global challenges

History and Nature of Science:

·        Science as a human endeavor

·        Nature of scientific knowledge


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